Which of the following fluoride gels requires a prescription?

The 2% sodium fluoride gel requires a prescription due to its higher concentration of fluoride, which is used primarily for patients at greater risk of developing caries. This higher potency makes it necessary for dental professionals to oversee its use, ensuring that patients use it safely and effectively. The prescription requirement also highlights the importance of monitoring fluoride intake, as excessive fluoride can lead to dental fluorosis or other health issues.

Other fluoride products, like 1.1% sodium fluoride, may be available over-the-counter for more general use in prevention, while lower concentrations, such as 0.25% fluoride gel, are also designed for preventive care without the need for a prescription. Topical fluoride varnish, though it is more concentrated than a gel and used in clinical settings, typically is applied in a controlled environment by a dental professional, which differentiates its use from that of higher concentration gels that necessitate individual prescriptions.